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Even optimal AOD-9604 protocols underperform when sleep is consistently inadequate

The overall short term complication rate for the laparoscopic approach is around 15-20% compared to 50-60% for the open approach

Testing for B12 levels can be a proactive way to prevent a deficiency

Add the reconstitution volume slowly along the vial wall rather than directing the stream onto the lyophilised cake, swirl gently until fully dissolved, and dont vortex as mechanical agitation can cause peptide and protein aggregation

Adults over 60 are at higher risk for low B12 status

Most side effects are short-lived and stop when injections are reduced or discontinued