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Alcohol and smoking may increase oxidative stress and may reduce the expected benefit of treatment

[DOI] [PubMed] [Google Scholar] 106.Zarei S., Carr K., Reiley L., Diaz K., Guerra O., Altamirano P.F., Pagani W., Lodin D., Orozco G., Chinea A

Hinton L, Franz CE, Reddy G, Flores Y, Kravitz RL, Barker JC

5-LOX overexpression exacerbates inflammation and neuronal damage after ischemia/reperfusion (I/R)

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Long-chain fatty acids must be esterified to L-carnitine (acylcarnitine) in order to enter the mitochondrial matrix where -oxidation occurs ( Figure 3 )