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THs are required for neuronal growth and function not only in the periphery but also in the CNS, 114 where they promote the formation of microglia, astrocytes, including radial glial cells, and oligodendrocytes

This process, known as demyelination, results in nerve cell damage

2013;14(4):674656 Fenton TR, Tough SC, Lyon AW, Eliasziw M, Hanley DA

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Validation of the RTOG recursive partitioning analysis (RPA) classification for brain metastases