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Metabolomics / Proteomics : High-throughput mass spectrometry technology can comprehensively analyze metabolites in cells, while metabolic flux analysis can track the dynamic changes of metabolites

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Considering that glutathione is involved in the elimination of harmful substances such as: alcohol, drugs, solvents, pesticides, heavy metals, and many other toxic xenobiotic products that induce a state of cellular stress [71], it is evident that glutathione homeostasis becomes more relevant, because cells require an antioxidant agent that either prevents or reduces this stress, whether by trapping, metabolizing or turning them into less toxic agents [71,101]

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2.5 Apparatus and parameters 2.5.1 LC-QTOF-MS/MS The parameters of LC-QTOF-MS/MS methods depended on the equipment on which the analyses were carried out