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In some formulations, a combination of a micronized therapeutic agent (and/or salt or prodrug thereof) and coated particles (e.g., nanoparticles, liposomes, microspheres) is used to prepare pulsed release otic formulations or compositions using any procedure described herein

In totality, it was observed that DSIP may help to bring about a normalized sleeping pattern and eliminate possible dysfunction in sleep cycles

2018;122(5):780-784.doi:10.1016/j.amjcard.2018.05.013 Fischer Walker C, Black RE

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