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Given the empirical and theoretical associations between BPD and loneliness, their shared genetic risks, the general health effects of loneliness, particularly in BPD, and the further segregation of those with increased symptoms early on, targeting loneliness as a general health intervention for those with BPD is critical
Notably, a proof-of-principle, randomized, double blind, placebo-controlled study of GS-9450 (selective inhibitor of caspases 1, 8, and 9) suggests that reducing hepatocellular apoptosis may be a valuable therapeutic strategy in patients with NASH (39)
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