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NNMT is heavily involved in the regulation of energy metabolism - its activity can promote fat storage and metabolic disorders

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The element is stored in the body mainly in the kidneys, spleen and testes, as well as in soft tissues, bones and blood, where it can bind to proteins, mainly transferrin

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This review provides an overview of current knowledge regarding the etiology, inducements, pathophysiology, and available treatments for migraine, with a focus on the clinical and experimental evidence of neurogenic inflammation and oxidative stress in migraine