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Description

Results Fragment-based drug design and chemistry Utilizing actives identified in a quantitative high-throughput screen against Schistosoma mansoni TGR 20,35 , 92 commercially available low molecular weight (MW) compounds/fragments were tested by X-ray crystallography 33,34,36

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ZeisbergMYangCMartinoMDuncanMBRiederFTanjoreHet alFibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition

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doi: 10.1038/s41418-019-0380-z 45 GaoMMonianPQuadriNRamasamyRJiangX

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Furthermore, NRF2 and PPAR engage in a reciprocal activation loop, enhancing each others transcription (Lee, 2017)

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