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This is well illustrated by the velocity equation for the CBS reaction, the first step in the transsulfuration pathway: The first factor is simply Michaelis-Menten kinetics for the CBS reaction that uses homocysteine (Hcy) and serine (Ser) as substrates

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[DOI] [PubMed] [Google Scholar] 76.Hurd TR, et al

For localized eczema, topical delivery targets affected areas directly with minimal systemic exposure