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If we include the patient who changed from sertraline (no effect) to citalopram (reasonable good effect), no significant difference remains (BF = 0.39) This is only anecdotal evidence that the mechanism via the sigma1 receptor plays a role in the action of SSRI in PCS
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Limosilactobacillus reuteri zy15 alleviates intestinal inflammation and barrier dysfunction via akt/mtor/hif-1/rort/il-17 signaling and the gut microbiota in etec k88-challenged mice