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Glutatyon vcut tarafndan sentezlenen endojen yani vcut tarafndan retilen bir molekldr ve vcuttaki glutatyon seviyesi yalanma, kt beslenme, evresel toksinlere maruziyet, sigara, stres ve baz hastalklar nedeniyle azalabilmektedir

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In humans, a decrease in GSH has been associated with different conditions, such as deficiency of the enzymes involved in glutathione synthesis [133]

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In AD animal models, M1-polarized microglia frequently co-exist with iron accumulation, indicating a synergistic interaction between inflammatory activation and disrupted iron metabolism in driving neurotoxicity (Mendoza and Scharff, 2017)