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Iron overload can lead to retinal inflammation through the downregulation of cholesterol efflux transporters, leading to increased cholesterol content in the retina (240)

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Nevertheless, substantial gaps in current research hinder a comprehensive understanding of lipid metabolism and antioxidant system-mediated ferroptosis regulation, as well as their translational application

In neuronal cells, A-induced toxicity is linked to increased oxidative stress, marked by elevated levels of ROS as well as increased activity and expression of NOX [79]

The pain radiated from the outside of my elbow down into my forearm, and gripping anything became a real chore

PMID 17602868