police, military, firefighters, paramedics, security guards, manual laborers like construction ) Athlete Plus is ideal for competitive athletes and marathon-level exertion Athlete Plus is recommended for individuals with prolonged exertion , DOMS (Delayed Onset Muscle Soreness) , or electrolyte depletion
Figure 26
T2D, non-alcoholic fatty liver disease (also known as metabolic dysfunction-associated steatotic liver disease) and hypertension diagnoses were all associated with lower weight loss efficacy, consistent with previous reports 22,23,24
Prostate cancer and melanoma experiments in mice were conducted in the BIOS+ animal facility in Bellinzona under specific pathogen-free conditions, with approval from project licences 35293, 36369 and 37480

Documented Long-Term Side Effects of Corticosteroids Bone loss and fractures due to calcium and vitamin D depletion and impaired osteoblast activity (2) Blood sugar dysregulation and steroid-induced diabetes through increased insulin resistance and gluconeogenesis (3) Muscle wasting and impaired connective tissue repair from protein catabolism and suppressed synthesis (4) Weakened immunity, delayed healing, and prolonged infections related to micronutrient depletion and immune suppression (5) Weight gain, mood changes, and insomnia driven by hormonal and circadian disruption (6,7) Abnormal blood lipids, hypertension, and increased cardiovascular risk , including heart attack, with long-term use (8) Thinning skin and easy bruising from collagen breakdown and connective tissue loss (9) Psychiatric effects , including anxiety, irritability, depression, andin severe casessteroid-induced psychosis, particularly at higher doses or with prolonged exposure (10) Even short-term corticosteroid use can cause side effects in susceptible patients

11shows immunohistochemistry images of explant cultures stained with Neurofilament (green), when incubated under different treatment (and time) conditions showing different number of surviving spiral ganglion neurons