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To prevent shelterin from dissociating into smaller subunits and to keep the complex intact during MP measurements, the samples were crosslinked after co-incubation with compounds, using 0.1% glutaraldehyde for 25 min at room temperature and quenched with 100 mM Tris-HCl pH 8.0 for 5 min (Supplementary Fig

doi: 10.3389/fsufs.2020.525810 124 HossainMSWazedMAAshaSHossenMAFimeSNMTeeyaSTet al

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Experts suggest using it at night

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Fragments with less than 20% peak intensity recovery in the presence of TRF1 TRFH and TIN2 TBM were classified as non-site-specific hits