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While the sample is small (6 patients), it represents an important step in the evidence chain: moving from laboratory proof-of-concept to human clinical testing

In phase II trials focusing on dermal applications, TB-500 has displayed promising outcomes for patients with pressure ulcers, stasis ulcers, and epidermolysis bullosa

Clear procedures reduce contamination risks during medication preparation routines

Unlike classical growth factors, BPC-157 exhibits a high degree of stability in gastric juice and oral bioavailability in animal studies, suggesting potential for systemic therapeutic effects

Absence of documentation should be considered a red flag

Since the majority of clinical trials are either in phase I or II, further evaluation and testing is needed regarding long term toxicity and potential adverse effects associated with those drugs (248252)