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Vascular endothelial dysfunction is the first step in atherosclerosis and plays an important role in the development, maintenance, and progression of atherosclerosis, resulting in cardiovascular events [5, 6]

Since most dippers tend to use tobacco more consistently than smokers, they actually get exposed to HIGHER levels of nicotine, which may result in higher levels of dependency

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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Andrade JG, Deyell MW, Macle L, Wells GA, Bennett M, Essebag V, Champagne J, Roux JF, Yung D, Skanes A, Khaykin Y, Morillo C, Jolly U, Novak P, Lockwood E, Amit G, Angaran P, Sapp J, Wardell S, , and Investigators E-A

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Nicotine & Tobacco Research, ntag030