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Rare risks include copper toxicity, particularly in individuals with underlying conditions such as Wilsons disease (a genetic disorder causing copper accumulation), and theoretical concerns regarding angiogenesis promotion in the context of active cancers

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Long-term corticosteroid use is associated with bone loss and increased risk of fracture

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Because TSP and OCM are central in many metabolic processes, such as methylation, GSH production, amino acid metabolism, and H 2 S production, the enzymes and metabolites may represent potential candidates for therapeutic targets

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