Because we cross Palomani Pass (17,060 ft), the highest point of the trek
The frequency depends on your health status, deficiency level, and health goals

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B12 shots are safe for most people, but those with certain health conditions should consult a doctor before starting treatment
Vitamin B12 injections are used to treat these by raising B12 levels and possibly fixing some nerve damage
If you use another B12 injection kit (hopefully not cyano B12), aim for at least 1 mg of B12 per shot, which is plenty