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While full-length hGH activates growth hormone receptors causing multiple effects (growth promotion, insulin resistance, lipolysis), AOD9604 is studied for its receptor-independent actions on fat cells

the signal comes from low-resolution post-market reports, while harder outcomes trend the other way. Does semaglutide preserve lean mass as well as tirzepatide

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AOD9604 has also been shown to have shown effects on heart disease through fat reduction and weight loss directly reducing the risk of heart disease

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Early and smaller studies suggested effects on fat metabolism and body fat distribution, but larger obesity trials did not show a robust, clinically meaningful weight loss outcome on their own